F-box and leucine-rich repeat 6 promotes gastric cancer progression via the promotion of epithelial-mesenchymal transition

Figure 4 Knockdown of F-box and leucine-rich repeat 6 in gastric cancer cells suppressed tumorigenesis invivo. A: Images of tumor formation in nude BALB/c mice after injection of sh-NC and sh-F-box and leucine-rich repeat 6 (FBXL6) #1 of HGC-27 cells into their subcutaneous; B: Tumor shape of shRNA and sh-NC groups after dissection; C: The tumor growth curve in sh-FBXL6#1 and sh-NC groups; D: Hematoxylin and eosin staining detected tumor in sh-FBXL6#1 and sh-NC groups; E and F: Immunohistochemical staining was performed to determine the tumor's expression of FBXL6, E-cadherin, N-cadherin, Vimentin, and Ki-67. ^bP < 0.01; ^cP < 0.001. FBXL6: F-box and leucine-rich repeat 6.