Machine learning algorithm to construct cuproptosis- and immune-related prognosis prediction model for colon cancer

Figure 5 External validation. Based on CDKN2A, HSPA1A, and UCN3, a cuproptosis- and immune-related prognostic model was constructed. In samples of The Cancer Genome Atlas (TCGA) database. A: Expression differences of these three genes in high- and low-risk groups and the risk score and survival time of different subgroups; B: KM curve indicates that the higher the score is, the worse the prognosis; C: Receiver operating characteristic curve shows that the model has area under the curve values greater than 0.6 in years 1, 3, and 5; D-F: In the Gene Expression Omnibus database, the model obtained similar results, and P < 0.05.