microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2

Figure 4 Cellular behaviours induced by microRNA-627-5p mimics and Wnt2 overexpression plasmids in SW480 and HCT116 cells. Experimental group: NC mimics, microRNA-627-5p (miR-627-5p) mimics, miR-627-5p mimics + pcDNA-Wnt2. A and D: Scratch assay was used to detect the migration of colorectal cancer (CRC) cells in each group; B and E: Matrigel invasion assay was used to detect the invasive capability of CRC cells in each group; C and F: Flow cytometry analysis was used to evaluate the apoptosis of CRC cells in each group; G: Cholecystokinin octapeptide (CCK-8) assay was used to detect the viability of CRC cells in each group. NS: Not significant; CRC: Colorectal cancer. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001.