Paired-related homeobox 1 induces epithelial-mesenchymal transition in oesophageal squamous cancer

Figure 5 Paired-related homeobox 1 regulates epithelial-mesenchymal transition via the WNT/β-catenin pathway. A: The protein levels of paired-related homeobox 1 (PRRX1), epithelial-mesenchymal transition (EMT) markers (E-cadherin, Vimentin, and N-cadherin), total β-catenin and nuclear β-catenin in different groups of EC109 and EC9706 cells (treated with 10 μM XAV939) were examined using western blotting; B: The protein levels of the EMT markers total β-catenin nuclear β-catenin, and PRRX1 in different groups of EC109 PRRX1(i) and EC9706 PRRX1(i) cells (treated with 20 mmol/L LiCl) were examined using western blotting. ^aP < 0.05. PRRX1: Paired-related homeobox 1.