Paired-related homeobox 1 induces epithelial-mesenchymal transition in oesophageal squamous cancer

Figure 3 Paired-related homeobox 1 modulates proliferation, colony formation, migration and invasion in oesophageal cancer cells. A: The MTT assay. Paired-related homeobox 1 (PRRX1) affected EC9706 cell proliferation; B: Soft agar colony formation assay. PRRX1 affected the ability of EC9706 cells to form colonies in soft agar, and the number of colonies was different in various groups of EC9706 cells; C: Cellular migration assays. PRRX1 affected the migration of EC9706 cells. The number of migrating EC9706 cells in various groups was different. Cells were stained with hematoxylin and eosin; D: Cellular invasion assays. PRRX1 affected the invasive properties of EC9706 cells. The number of invasive EC9706 cells in various groups was different. Cells were stained with hematoxylin and eosin. ^aP < 0.05. PRRX1: Paired-related homeobox 1.