Hsa_circ_0136666 mediates the antitumor effect of curcumin in colorectal carcinoma by regulating CXCL1 via miR-1301-3p

doi:10.4251/wjgo.v15.i12.2120

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Dec 15, 2023 (publication date) through Jul 27, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2023; 15(12): 2120-2137
Published online Dec 15, 2023. doi: 10.4251/wjgo.v15.i12.2120

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Figure 3 Upregulating hsa_circ_0136666 overturned curcumin-mediated apoptosis promotion in colorectal carcinoma cells. SW480 and SW620 were treated with DMSO, curcumin, curcumin + vector, and curcumin + oe-hsa_circ_0136666. A and B: Flow cytometry assays tested apoptosis rate in treated SW480 and SW620; C and D: Western blot assays determined Bcl-2 and Bax protein levels in treated SW480 and SW620. ¹P < 0.05.

Citation: Chen S, Li W, Ning CG, Wang F, Wang LX, Liao C, Sun F. Hsa_circ_0136666 mediates the antitumor effect of curcumin in colorectal carcinoma by regulating CXCL1 via miR-1301-3p. World J Gastrointest Oncol 2023; 15(12): 2120-2137
URL: https://www.wjgnet.com/1948-5204/full/v15/i12/2120.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i12.2120