Hsa_circ_0136666 mediates the antitumor effect of curcumin in colorectal carcinoma by regulating CXCL1 via miR-1301-3p

Figure 2 Overexpressing hsa_circ_0136666 overturned the effect of curcumin on proliferation in colorectal carcinoma SW480 and SW620 cells. Colorectal carcinoma cells were treated with DMSO, curcumin, curcumin + vector, and curcumin + oe-hsa_circ_0136666. A: Cell counting kit-8 assays examined SW480 and SW620 cell viability after treatment; B and C: Colony-forming cell assays detected colony numbers in treated SW480 and SW620; D and E: 5-Ethynyl-2’-deoxyuridine assays measured positive cells in treated SW480 and SW620; F and G: Flow cytometry assays analyzed cell cycle distribution in treated SW480 and SW620. ¹P < 0.05.