Hsa_circ_0136666 mediates the antitumor effect of curcumin in colorectal carcinoma by regulating CXCL1 via miR-1301-3p

Figure 1 The impacts of curcumin treatment on colorectal carcinoma (SW480 and SW620) cell proliferation and apoptosis. Colorectal carcinoma (CRC) cells were treated with DMSO or curcumin (20 μM). A: Cell viability was detected in treated or untreated SW480 and SW620 using cell counting kit-8 assays; B and C: Colony number assessment by colony-forming cell assays in treated or untreated SW480 and SW620; D and E: Apoptosis rate analysis in treated or untreated CRC cells by flow cytometry assays; F: Real-time quantitative PCR analysis of hsa_circ_0000392, hsa_circ_0000896, and hsa_circ_0136666 expression in treated or untreated SW480 and SW620 cells. ¹P < 0.05.