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©The Author(s) 2023.
World J Gastrointest Oncol. Dec 15, 2023; 15(12): 2053-2063
Published online Dec 15, 2023. doi: 10.4251/wjgo.v15.i12.2053
Published online Dec 15, 2023. doi: 10.4251/wjgo.v15.i12.2053
Target genes silenced by siRNA (under investigation) | Target genes for GBC treatment (under clinical trial) |
BMI1, CD44, CLIC1, JAB1, EGFR | EGFR and Her/2 together (Afatnib-NCT04183712, Apatinib-NCT03702491) |
HER 2/neu, ARAF | HER/2 (Trastuzumab-NCT00478140) |
MIF | MEK (Trametinib-NCT02042443) |
CD73, PDL1 | DNMT (Guadecitabine-NCT03257761) |
- Citation: Ghosh I, Dey Ghosh R, Mukhopadhyay S. Identification of genes associated with gall bladder cell carcinogenesis: Implications in targeted therapy of gall bladder cancer. World J Gastrointest Oncol 2023; 15(12): 2053-2063
- URL: https://www.wjgnet.com/1948-5204/full/v15/i12/2053.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v15.i12.2053