Application of sintilimab combined with anlotinib hydrochloride in the clinical treatment of microsatellite stable colorectal cancer

doi:10.4251/wjgo.v15.i11.1925

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Nov 15, 2023; 15(11): 1925-1935
Published online Nov 15, 2023. doi: 10.4251/wjgo.v15.i11.1925

Table 3 Comparison of serum carcinoembryonic antigen, carbohydrate antigen 199, and carbohydrate antigen 125 levels

Indicators	Time	Observation group, n = 46	Control group, n = 46	t	P value
CEA in ng/mL	Before treatment	119.16 ± 18.54	120.06 ± 18.91	0.230	0.818
CEA in ng/mL	After treatment	52.17 ± 7.40¹	71.24 ± 10.22¹	110.250	0.000
CA199 in IU/mL	Before treatment	120.16 ± 20.41	120.55 ± 20.59	0.091	0.928
CA199 in IU/mL	After treatment	51.37 ± 10.22¹	62.47 ± 14.04¹	4.335	0.000
CA125 in U/mL	Before treatment	247.56 ± 25.47	246.91 ± 25.21	0.123	0.902
CA125 in U/mL	After treatment	69.14 ± 10.09¹	88.15 ± 14.53¹	7.288	0.000

¹Denotes a comparison with the pre-treatment values. Data are mean ± SD. CA: Carbohydrate antigen; CEA: Carcinoembryonic antigen.

Citation: Feng R, Cheng DX, Chen XC, Yang L, Wu H. Application of sintilimab combined with anlotinib hydrochloride in the clinical treatment of microsatellite stable colorectal cancer. World J Gastrointest Oncol 2023; 15(11): 1925-1935
URL: https://www.wjgnet.com/1948-5204/full/v15/i11/1925.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i11.1925