Pomolic acid and its glucopyranose ester promote apoptosis through autophagy in HT-29 colon cancer cells

Figure 4 Effects of pomolic acid and pomolic acid-28-O-β-D-glucopyranosyl ester on the relative expression of proteins. A and B: The expression of apoptosis related protein in HT-29 cells treated with pomolic acid (PA) for 24 h and 48 h; C and D: The expression of autophagy related protein in HT-29 cells treated with PA for 24 h and 48 h; E and F: The expression of signal transducer and activator of transcription 3 (STAT3) and janus kinase (JAK) protein in HT-29 cells treated with PA for 24 h and 48 h; G and H: The expression of apoptosis related protein in HT-29 cells treated with pomolic acid-28-O-β-D-glucopyranosyl ester (PAO) for 24 h and 48 h; I and J: The expression of p62 protein in HT-29 cells treated with PAO for 24 h and 48 h; K: The expression of STAT3 and JAK1 protein in HT-29 cells treated with PAO for 24h; L: The expression of STAT3 protein in HT-29 cells treated with PAO for 48 h. Caspase: Cysteinyl aspartate specific proteinase; LC3: Light chain 3; STAT3: Signal transducer and activator of transcription 3; JAK: Janus kinase.