Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA vaccine development

doi:10.4251/wjgo.v15.i10.1717

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Oct 15, 2023 (publication date) through Nov 23, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2023; 15(10): 1717-1738
Published online Oct 15, 2023. doi: 10.4251/wjgo.v15.i10.1717

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Figure 8 Association between immune subtypes and immune checkpoint/immune cell death modulator-related genes. A and B: Box plot of differential expression of immune checkpoint genes among immune subtypes in the The Cancer Genome Atlas (TCGA) (A) and International Cancer Genome Consortium (ICGC) (B) cohorts; C and D: Box plot of differential expression of immune cell death modulator genes among immune subtypes in the TCGA (C) and ICGC (D) cohorts. ^aP value < 0.05; ^bP value < 0.01; ^cP value < 0.001; ^dP value < 0.0001; NS: Not significant.

Citation: Lu TL, Li CL, Gong YQ, Hou FT, Chen CW. Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA vaccine development. World J Gastrointest Oncol 2023; 15(10): 1717-1738
URL: https://www.wjgnet.com/1948-5204/full/v15/i10/1717.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i10.1717