Synchronous occurrence of gastric cancer and gastrointestinal stromal tumor: A case report and review of the literature

Table 2 The clinical, histological and immunohistochemical characteristics of gastrointestinal stromal tumor in 19 patients

No.	CT	EGD	Location	Origin	Size (cm)	Type	Growth pattern	Mitotic index (HPF)	Risk category	CD117	CD34	Dog-1	S-100	SMA	VIM	IM
1	GIST	GIST	Antrum	Submucosal	9.0	Spindle, epithelioid	Intraluminal	< 5/50	High	+	+	+	-	-	NA	Yes
2	(-)	(-)	Body	Muscularis	0.4	NA	Intramural	< 5/50	Very low	++	+++	+++	-	-	NA	No
3	(-)	(-)	Body	Subserous	1.0	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
4	Mass	(-)	Duodenum	NA	2.0	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
5	(-)	(-)	Jejunum	NA	1.5	Spindle	Extraluminal	< 5/50	Low	++	+	+++	-		NA	No
6	(-)	GIST	Fundus	Muscularis	1.5	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
7	GIST	GIST	Body	NA	5.0	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
8	Mass	Mass	Fundus	Subserous	1.0	Spindle	Intraluminal	< 5/50	Low	+	+	+	-	NA	NA	No
9	(-)	Mass	Duodenum	NA	4.0	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
10	(-)	(-)	Cardia	Subserous	0.2	Spindle	Extraluminal	< 5/50	Very low	+	+	+	-	-	NA	No
11	GIST	GIST	Body	Muscularis	12.0	Spindle	Extraluminal, intraluminal	6-10/50	High	+	+	+	-	-	+	Yes
12	(-)	(-)	Jejunum	NA	4.0	Spindle	Extraluminal	< 5/50	Low	+	-	+	-	-	+	No
13	(-)	(-)	Body	Muscularis	0.4	Spindle	Intramural	< 5/50	Very low	+	+	+	-	-	NA	No
14	(-)	(-)	Fundus	Subserous	0.4	Spindle	Extraluminal	< 5/50	Very low	++	+++	+++	-	NA	NA	No
15	(-)	(-)	Body	Submucosal	0.6	Spindle	Intramural	< 5/50	Very low	+	+	+	-	-	NA	No
16	(-)	(-)	Body	Subserous	3.0.	Spindle	Extraluminal	< 5/50	Low	+	+	+	-	-	+	No
17	(-)	(-)	Antrum	Muscularis	< 1.0	NA	Intramural	< 5/50	Very low	+	+	NA	NA	NA	NA	No
18	(-)	(-)	Cardia, fundus	Subserous	0.4	Spindle	Extraluminal	< 5/50	Low	+	+	+	NA	-	NA	No
19	(-)	(-)	Body	Subserous	1.3	Spindle	Extraluminal	< 5/50	Very low	+	+	-	-	NA	+	No

NA: Not assessed; CT: Computed tomography; EGD: Esophagogastroduodenoscopy; V-L: Very low; L: Low; IN: Intermediate; H: High; IM: Imatinib mesylate; GC: Gastric cancer; GIST: Gastrointestinal stromal tumor.