Synchronous occurrence of gastric cancer and gastrointestinal stromal tumor: A case report and review of the literature

Table 1 Clinicopathological features, treatment and outcome of gastric cancer in 19 patients

No.	Age in yr	Sex	BMI	Chief complaint	Disease duration (mo)	Comorbidities in yr	Tumor marker	Primary site	Size (cm)	pTNM	Gross appearance	Differentiation	Lauren type	Outcome
1	66	M	17.9	Epigastric discomfort	12.0	HBP/20	(-)	Pylorus	1.5	T3N0M0/IIA	Ulcerativeinfiltrative	M-P	Mixed	38 m, PFS
2	56	M	24.2	CT found by accident	2.0	No	(-)	Cardia, body, antrum	10.0	T3N1M0/IIB	Diffuse infiltrative	P, SRCC	Diffuse	NA
3	53	M	19.5	Upper abdominal pain	0.5	No	CA72-4↑	Body	4.5	T3N0M0/IIA	Ulcerative infiltrative	P, SRCC	NA	48 m, PFS
4	71	M	21.5	Epigastric discomfort	6.0	No	(-)	Body	2.0	T2N0M0/IB	NA	M-P	Mixed	53 m, PFS
5	45	M	21.8	Bloating, acid reflux	6.0	No	(-)	Pylorus	3.5	T3N2M0/IIIA	Ulcerative	M-P, SRCC	Diffuse	48 m, DOD
6	55	M	25.5	Epigastric discomfort	2.0	No	(-)	Antrum	4.0	T1bN0M0/IA	Ulcerative	M-P, SRCC	Intestinal	6 m, PFS
7	79	F	22.2	Heartburn, abdominal pain, black stools	2.0	HBP/10, DM/10	(-)	Antrum	3.0	TisN0M0/0	NA	HGIEN	NA	27 m, PFS
8	58	M	27.9	Upper abdominal pain	4.0	No	(-)	Antrum	5.0	T4aN0M0/IIB	Ulcerative	P	Diffuse	26 m, PFS
9	71	M	23.8	Epigastric pain, acid reflux	1.0	HBP/10	(-)	Antrum	3.5	T1bN0M0/IA	NA	M	Intestinal	23 m, PFS
10	56	M	23.2	Upper abdominal pain, choking eating, black stools	1.0	No	(-)	Cardia	1.5	T2N0M0/IB	Ulcerative infiltrative	M	Intestinal	NA
11	55	M	23.7	Abdominal distension	9.0	No	CEA↑	Fundus	3.0	T4aN3bM0/IIIC	Ulcerative	M	Intestinal	10 m, DOD
12	59	M	23.1	Abdominal distension, black stools	1.0	DM/6	(-)	Body	5.0	T2N0M0/IB	Ulcerative	P	Diffuse	20 m, PFS
13	62	M	22.9	Upper abdominal pain	12.0	No	CEA↑, CA724↑	Body	2.0	T3N0M0/IIA	Ulcerative	P, SRCC	Diffuse	9 m, PFS
14	49	M	13.1	Epigastric discomfort	12.0	No	(-)	Cardia, fundus	5.0	T4bN0M0/IIIA	Ulcerative	M-P	Mixed	45 m, PFS
15	65	F	23.6	Epigastric discomfort, abdominal distension	12.0	No	(-)	Cardia, body	2.5	T4aN1M0/IIIA	Ulcerative	M	NA	5 m, DOD
16	73	M	21.3	Epigastric discomfort	48.0	No	CA724↑	Body	5.0	T4aN3bM0/IIIC	Ulcerative	M-P	Diffuse	12 m, DOD
17	62	M	22.8	Upper abdominal pain	6.0	DM/6	CEA↑, CA125↑	Antrum	3.5	T4aN0M0/IIB	Ulcerative infiltrative	M	Intestinal	70 m, PFS
18	62	M	21.2	Progressive dysphagia	3.0	HBP/30	CA199↑	Cardia	4.5	T4aN2M0/IIIA	Ulcerative	M-P	Mixed	12 m, DOD
19	72	M	22.4	Upper abdominal pain	0.5	No	(-)	Body	1.5	T1bN0M0/IA	NA	W	NA	63 m, PFS

M: Male; F: Female; HBP: High blood pressure; DM: Diabetes Mellitus (Type 2); TG: Total gastrectomy; DG: Distal gastrectomy; PG: Proximal gastrectomy; pTNM: Pathological tumor-node-metastasis; SRCC: Signet-ring cell carcinoma; HGIEN: High-grade intraepithelial neoplasia; NA: Not assessed; PFS: Progression-free survival; DOD: Dead of disease; M-P: Moderately to poorly differentiated; M: Moderately differentiated; P: Poorly differentiated; W: Well differentiated.