Surgical treatments of recurrent small intestine metastatic melanoma manifesting with gastrointestinal hemorrhage and intussusception: A case report

Figure 3 Histopathological findings of the resected small intestine after the first surgery. A: Representative specimen showing diffuse growth of tumor tissue, the majority located in the submucosa and nearly invading the mucosa (yellow rectangle). Hematoxylin and eosin, × 4; B: Tumor cells were distributed in a patchy pattern. Hematoxylin and eosin, × 10; C: The lesions had large nuclei, prominent nucleoli, and red cytoplasm. Some tumor cells showed pigment granules in the cytoplasm (green arrows). Hematoxylin and eosin, × 20; D: At high power, epithelioid tumor cells contained mitotic figures (yellow arrows). Hematoxylin and eosin, × 40.