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©The Author(s) 2023.
World J Gastrointest Oncol. Jan 15, 2023; 15(1): 128-142
Published online Jan 15, 2023. doi: 10.4251/wjgo.v15.i1.128
Published online Jan 15, 2023. doi: 10.4251/wjgo.v15.i1.128
Table 2 Univariate and multivariate logistic analyses of liver metastasis in pancreatic cancer patients, n (%)
Variable | Levels | Without LM (n = 14608) | With LM (n = 7698) | Univariate analysis (OR, 95%CI) | Multivariate analysis (OR, 95%CI) |
Age at diagnosis (yr) | ≤ 70 | 8783 (60.1) | 5032 (65.4) | ||
> 70 | 5825 (39.9) | 2666 (34.6) | 0.80 (0.75-0.85, P < 0.001) | 0.72 (0.68-0.77, P < 0.001) | |
Sex | Female | 7393 (50.6) | 3485 (45.3) | ||
Male | 7215 (49.4) | 4213 (54.7) | 1.24 (1.17-1.31, P < 0.001) | 1.16 (0.89-1.23, P = 0.056) | |
Race | White | 11590 (79.3) | 6048 (78.6) | ||
Black | 1730 (11.8) | 1047 (13.6) | 1.16 (1.07-1.26, P < 0.001) | 1.07 (0.97-1.17, P = 0.186) | |
Other | 1288 (8.8) | 603 (7.8) | 0.90 (0.81-0.99, P = 0.036) | 0.93 (0.83-1.04, P = 0.228) | |
Primary site | Head | 8939 (61.2) | 3003 (39) | ||
Body/tail | 3604 (24.7) | 3212 (41.7) | 2.65 (2.49-2.83, P < 0.001) | 2.30 (2.14-2.47, P < 0.001) | |
Other | 2065 (14.1) | 1483 (19.3) | 2.14 (1.98-2.31, P < 0.001) | 1.76 (1.61-1.92, P < 0.001) | |
Histology | Adenocarcinoma | 9394 (64.3) | 5867 (76.2) | ||
Neuroendocrine carcinoma | 640 (4.4) | 411 (5.3) | 1.03 (0.90-1.17, P = 0.670) | 1.28 (1.10-1.49, P = 0.001) | |
Other | 4574 (31.3) | 1420 (18.4) | 0.50 (0.46-0.53, P < 0.001) | 0.61 (0.56-0.66, P < 0.001) | |
Pathological grade | Well/moderate | 4727 (32.4) | 799 (10.4) | ||
Poor/anaplastic | 2476 (16.9) | 919 (11.9) | 2.20 (1.97-2.44, P < 0.001) | 2.26 (2.01-2.53, P < 0.001) | |
Unspecific | 7405 (50.7) | 5980 (77.7) | 4.78 (4.40-5.19, P < 0.001) | 4.23 (3.86-4.64, P < 0.001) | |
T stage | T1 | 1131 (7.7) | 245 (3.2) | ||
T2 | 2901 (19.9) | 2653 (34.5) | 4.22 (3.65-4.90, P < 0.001) | 1.53 (0.89-1.86, P = 0.080) | |
T3 | 7325 (50.1) | 2402 (31.2) | 1.51 (1.31-1.75, P < 0.001) | 0.81 (0.64-1.02, P = 0.054) | |
T4 | 3019 (20.7) | 1411 (18.3) | 2.16 (1.86-2.52, P < 0.001) | 0.72 (0.56-1.01, P = 0.051) | |
TX | 232 (1.6) | 987 (12.8) | 9.4 (6.4-9.7, P < 0.001) | 7.18 (5.52-9.35, P < 0.001) | |
LN metastasis | No | 8213 (56.2) | 4046 (52.6) | ||
Yes | 6395 (43.8) | 3652 (47.4) | 1.16 (1.10-1.23, P < 0.001) | 1.38 (1.30-1.47, P < 0.001) | |
Tumor size (cm) | < 2 | 1966 (13.5) | 460 (6) | ||
2-4 | 6800 (46.5) | 2939 (38.2) | 1.85 (1.66-2.06, P < 0.001) | 1.29 (1.08-1.55, P = 0.006) | |
> 4 | 5842 (40) | 4299 (55.8) | 3.15 (2.82-3.51, P < 0.001) | 2.05 (1.71-2.46, P < 0.001) |
- Citation: Cao BY, Tong F, Zhang LT, Kang YX, Wu CC, Wang QQ, Yang W, Wang J. Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis. World J Gastrointest Oncol 2023; 15(1): 128-142
- URL: https://www.wjgnet.com/1948-5204/full/v15/i1/128.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v15.i1.128