Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data

Figure 4 Ingenuity pathway analysis of homeobox A10 activity in hepatitis B-related hepatocellular carcinoma. Homeobox A10 signaling has potential implications on tumor suppression, liver metabolism, and other disease-related activity. Genes and location are shown above. Legend illustrates relationship between genes and gene classification. COL15A1: Collagen alpha-1(XV) chain; IGFBP3: Insulin-like growth factor binding protein 3; DKK1: Dickkopf-related protein 1; CFD: Complement factor D; LEPR: Leptin receptor; BCHE: Butyrylcholinesterase; THBD: Thrombomodulin; SFRP4: Secreted frizzled-related protein 4; ALPL: Alkaline phosphatase; CYP2E1: Cytochrome P450 2E1; TDO2: Tryptophan 2,3-dioxygenase; NDRG2: N-myc downstream-regulated gene family member 2; GSTA3: Glutathione S-transferase A3; PHGDH: Phosphoglycerate dehydrogenase; XDH: Xanthine dehydrogenase; INMT: Indolethylamine N-methyltransferase; SCD: Stearoyl-CoA desaturase; HBG1: Hemoglobin subunit gamma 1; ADH4: Alcohol dehydrogenase 4; HOXA10: Homeobox A10; THRSP: Thyroid hormone-inducible hepatic protein. Citation: Figures produced from IPA are available under an open-access CC-BY 4.0 license for purposes of publication. The authors have obtained the permission for figure using from the QIAGEN Digital Insights (Supplementary material).