Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data

Figure 3 Ingenuity pathway analysis of rab-like protein 6 signaling in hepatitis B-related hepatocellular carcinoma tumors. Genes are implicated in several disease potential disease processes including inflammation, cell division, Akt signaling, and more. Legend illustrates relationship between genes. See Figure 2 legend for identification of shapes. RABL6: RAB, member RAS oncogene family like 6; TP53: Tumor protein p53; E2F4: E2F transcription factor 4; FOXO1: Forkhead box O1; FOXM1: Forkhead box M1; MCM10: Mini-chromosome maintenance 10; BUB1: Mitotic checkpoint serine/threonine-protein kinase BUB1; TTK: TTK protein kinase; UBE2C: Ubiquitin-conjugating enzyme E2 C; TOP2A: DNA topoisomerase IIα; CCNA2: Cyclin A2; CENPF: Centromere protein F; EZH2: Enhancer of zeste homolog 2; NEK2: Serine/threonine-protein kinase Nek2. Citation: Figures produced from IPA are available under an open-access CC-BY 4.0 license for purposes of publication. The authors have obtained the permission for figure using from the QIAGEN Digital Insights (Supplementary material).