Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data

Figure 2 Top network (cell cycle; cellular assembly and organization; DNA replication, recombination and repair) identified by ingenuity pathway analysis Network analysis. Legend illustrates class of the gene. Red indicates upregulation and green downregulation, with shade depicting magnitude of change. Solid and dashed lines depict direct and indirect, respectively, relationship between genes. Figure was generated using ingenuity pathway analysis. TENM1: Teneurin transmembrane protein 1; GGT5: Gamma-glutamyltransferase5; SLC1A4: Solute carrier family 1 member 4; OVOS2: Alpha-2-macroglobulin like 1 pseudogene; XK: X-linked Kx blood group; WHRN: Whirlin; MPC1: Mitochondrial pyruvate carrier 1; LILRB5: Leukocyte immunoglobulin like receptor B5; CNDP1: Carnosine dipeptidase 1; CENPM: Centromere protein M; CENPL: Centromere protein L; ESR1: Estrogen receptor 1; C4BP: C4b-binding protein; TUFT1: Tuftelin 1; DSN1: MIND kinetochore complex component; KNL1: Kinetochore scaffold 1; BUB1: Mitotic checkpoint serine/threonine-protein kinase BUB1; HPS5: Hermansky-Pudlak syndrome 5 protien; FCN3: Ficolin 3; MASP1: MBL associated serine protease 1; MBL2: Mannose binding lectin 2; HIST1H2BF: Histone H2B type 1; OIP5: Opa interacting protein 5; NDC80: Kinetochore protein NDC80; BUB1B: BUB1 mitotic checkpoint serine/threonine kinase B; MND1: Meiotic nuclear divisions 1; CENPW: Centromere protein W; CENPH: Centromere protein H; CENPK: Centromere protein K; CENPA: Centromere protein A. Citation: Figures produced from IPA are available under an open-access CC-BY 4.0 license for purposes of publication. The authors have obtained the permission for figure using from the QIAGEN Digital Insights (Supplementary material).