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©The Author(s) 2022.
World J Gastrointest Oncol. Sep 15, 2022; 14(9): 1874-1886
Published online Sep 15, 2022. doi: 10.4251/wjgo.v14.i9.1874
Published online Sep 15, 2022. doi: 10.4251/wjgo.v14.i9.1874
Ref. | Country | Sample size | TNM stage | Detection method | Antibody | Method of quantification | Cut-off value | Positive proportion (%) | Outcome | Source of HR | Follow-up time (mo) | NOS score |
Sasaki et al[11], 2009 | Japan | 166 | I-IV | IHC | Anti-Twist (sc-15393, Santa Cruz) | Multiply percentage score and intensity score | Low: 0-5; High: 6-7 | 40.2 | OS | R | 24 (1-181) | 8 |
Xie et al[12], 2009 | China | 112 | I-IV | IHC | Anti-Twist (sc-15393, Santa Cruz) | Multiply percentage score and intensity score | Negative: 0-3; Positive: 4-5+; 6-8++; ≥ 9+++ | 79.5 | OS | R | 35.8 (3.4-87) | 7 |
Lee et al[13], 2012 | South Korea | 165 | I-IV | IHC/RT-PCR | Anti-Twist1 (ab50887, Abcam) | Intensity score | Negative: No expression; Positive: Weak, moderate, strong | 50.9 | OS/DFS | R/E | 115 (2-155) | 6 |
Nakajima et al[14], 2012 | Japan | 54 | I-IVA | IHC | Anti-Twist (sc-15393, Santa Cruz) | Intensity score | Faint: 1; Moderate: 2; Strong: 3 | 37 | OS/RFS | R | NA | 7 |
Sun et al[15], 2013 | China | 164 | I-III | IHC | Anti-Twist1 (ab50887, Abcam) | Percentage of stained cells | Negative: 0%-10%; Positive: > 10% | 34.1 | OS | E | 96-120 | 7 |
Chen et al[16], 2016 | China | 50 | NR | IHC | Anti-Twist1 (Abcam) | Percentage of stained cells | NA | 50 | OS | E | > 60 | 7 |
Yeo et al[17], 2017 | Korea | 169 | I-IV | IHC | Anti-Twist1 (Abcam) | Intensity score | Negative: 1; Positive: 2-3 | 89.9 | OS/DFS | R | NA | 7 |
Xu et al[18], 2021 | China | 229 | I-IV | IHC | Anti-Twist1 (ab175430; Abcam) | Multiply percentage score and intensity score | Negative: 0-5; Positive: ≥ 6 | 59 | OS/PFS | E | NA | 6 |
Du et al[19], 2021 | China | 72 | I-III | IHC | Anti-Twist (bs-2441R, Bioss) | Multiply percentage score and intensity score | Negative: 0-2; Positive: ≥ 3 | 61.1 | OS | E | 14-90 | 6 |
Tang et al[20], 2021 | China | 40 | II-IV | IHC | Anti-Twist1 (ab50581, Abcam) | Multiply percentage score and intensity score | Negative: 0-2; Positive: ≥ 3 | 15 | OS | R | 17 (13.9-20.1) | 7 |
Wang et al[21], 2021 | China | 72 | I-III | IHC | Anti-Twist1 (bs-2441R, Bioss) | Multiply percentage score and intensity score | Negative: 0-3; Positive: ≥ 4 | 61.1 | OS | E | 14-90 | 6 |
- Citation: Song WP, Wang SY, Zhou SC, Wu DS, Xie JY, Liu TT, Wu XZ, Che GW. Prognostic and clinicopathological value of Twist expression in esophageal cancer: A meta-analysis. World J Gastrointest Oncol 2022; 14(9): 1874-1886
- URL: https://www.wjgnet.com/1948-5204/full/v14/i9/1874.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v14.i9.1874