Meta-Analysis
Copyright ©The Author(s) 2022.
World J Gastrointest Oncol. Sep 15, 2022; 14(9): 1874-1886
Published online Sep 15, 2022. doi: 10.4251/wjgo.v14.i9.1874
Table 1 Basic characteristics of included studies
Ref.
Country
Sample size
TNM stage
Detection method
Antibody
Method of quantification
Cut-off value
Positive proportion (%)
Outcome
Source of HR
Follow-up time (mo)
NOS score
Sasaki et al[11], 2009Japan166I-IVIHCAnti-Twist (sc-15393, Santa Cruz)Multiply percentage score and intensity scoreLow: 0-5; High: 6-740.2OSR24 (1-181)8
Xie et al[12], 2009China112I-IVIHCAnti-Twist (sc-15393, Santa Cruz)Multiply percentage score and intensity scoreNegative: 0-3; Positive: 4-5+; 6-8++; ≥ 9+++79.5OSR35.8 (3.4-87)7
Lee et al[13], 2012South Korea165I-IVIHC/RT-PCRAnti-Twist1 (ab50887, Abcam)Intensity scoreNegative: No expression; Positive: Weak, moderate, strong50.9OS/DFSR/E115 (2-155)6
Nakajima et al[14], 2012Japan54I-IVAIHCAnti-Twist (sc-15393, Santa Cruz)Intensity scoreFaint: 1; Moderate: 2; Strong: 337OS/RFSRNA7
Sun et al[15], 2013China164I-IIIIHCAnti-Twist1 (ab50887, Abcam)Percentage of stained cellsNegative: 0%-10%; Positive: > 10%34.1OSE96-1207
Chen et al[16], 2016China50NRIHCAnti-Twist1 (Abcam)Percentage of stained cellsNA50OSE> 607
Yeo et al[17], 2017Korea169I-IVIHCAnti-Twist1 (Abcam)Intensity scoreNegative: 1; Positive: 2-389.9OS/DFSRNA7
Xu et al[18], 2021China229I-IVIHCAnti-Twist1 (ab175430; Abcam)Multiply percentage score and intensity scoreNegative: 0-5; Positive: ≥ 659OS/PFSENA6
Du et al[19], 2021China72I-IIIIHCAnti-Twist (bs-2441R, Bioss)Multiply percentage score and intensity scoreNegative: 0-2; Positive: ≥ 361.1OSE14-906
Tang et al[20], 2021China40II-IVIHCAnti-Twist1 (ab50581, Abcam)Multiply percentage score and intensity scoreNegative: 0-2; Positive: ≥ 315OSR17 (13.9-20.1)7
Wang et al[21], 2021China72I-IIIIHCAnti-Twist1 (bs-2441R, Bioss)Multiply percentage score and intensity scoreNegative: 0-3; Positive: ≥ 461.1OSE14-906