Clinicopathological characterization of ten patients with primary malignant melanoma of the esophagus and literature review

Table 3 Correlation between lymph node metastasis and clinicopathological features

Feature	LNM-		LNM+		P valve	Logistic regression analysis
	n	%	n	%		P valve	OR (95%CI)
Gender
Male	77	51.0	74	49.0	0.307
Female	25	43.1	33	56.9
Age (yr)	59.4 ± 8.9		57.2 ± 10.3		0.109
Location
Upper	3	75.0	1	25.0	0.202
Middle	52	53.6	45	46.4
Lower	47	43.5	61	56.5
Tumor size (cm)	4.6 ± 2.4		6.0 ± 3.0		< 0.001	0.006	1.21 (1.05-1.38)
Tumor number
Single	23	41.1	33	58.9	0.919
Multiple	14	40.0	21	60.0
Censored	67	54.5	56	46.5
Gross classification
Superficial elevated	11	91.7	1	8.3	0.01	0.261
Polypoid	68	46.6	78	53.4
Ulcerative and others	14	45.2	17	54.8
Censored	9	45	11	55
Infiltration depth
T1a	14	100	0	0	< 0.001	< 0.001	2.22 (1.47-3.33)
T1b	40	54.8	33	45.2
T2	30	48.4	32	51.6
T3 + T4	9	20.0	36	80.0
Censored	9	60	6	40

LNM: Lymph node metastases; OR: Odds ratio; CI: Confidence interval.