Clinicopathological characterization of ten patients with primary malignant melanoma of the esophagus and literature review

Table 2 Clinicopathologic characteristics of 290 primary malignant melanoma of esophagus patients

Characteristic	n	%
Gender
Male	200	69.0
Female	90	31.0
Age	58.4 ± 9.7 yr
Symptoms
Dysphagia	219	79.1
Restrosternal pain	13	4.7
Dysphagia and restrosternal pain	18	6.5
Bellyache	11	4.0
No symptom found by physical examination	8	2.9
Loss of appetite	6	2.2
Hoematemesis or melena	2	0.7
Censored	13
Location
Upper	16	5.4
Middle	137	47.3
Lower	137	47.3
Pigmentation
Yes	141	71.9
No	55	28.1
Censored	94
Pathological diagnosis of biopsy
PMME	115	55.8
ESCC	32	15.5
Poorly differentiated carcinoma	39	18.9
Esophageal adenocarcinoma	10	4.9
High-grade dysplasia or non-neoplastic lesions	10	4.9
Censored	84
Treatment
Surgery	153	58.8
Surgery and adjuvant treatment	88	35.1
Adjuvant treatment	16	6.1
Censored	33
Tumor size (censored: n = 77)	5.2 ± 2.9 cm
Tumor number
Single	74	61.7
Multiple	46	38.3
Censored	170
Gross classification
Superficial elevated	14	5.7
Polypoid	194	77.9
Ulcerative and others	36	14.4
Censored	46
Depth of invasion
T1	97	45.6
T2	67	31.4
T3 and T4	49	23.0
Censored	77
Lymph node metastasis
Yes	107	51.2
No	102	48.8
Censored	81