Efficacy and safety of computed tomography-guided microwave ablation with fine needle-assisted puncture positioning technique for hepatocellular carcinoma

Table 2 Factors associated with local tumor progression

Factors	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Sex	0.706 (0.166, 2.966)	0.637
Age (yr): > 60; 60	1.041 (0.486, 2.229)	0.918
ECOG PS: 0; 1	3.169 (1.197, 8.392)	0.020	2.979 (1.108, 8.014)	0.031
Tumor number: 1; 2-3	3.370 (1.561, 7.277)	0.002	3.008 (1.383, 6.546)	0.005
AFP (ng/mL): < 400; ≥ 400	0.601 (0.142, 2.538)	0.488
Tumor size (cm): < 3; 3-5	1.649 (0.754, 3.603)	0.210
Auxiliary TACE pre-MWA: Yes; No	1.232 (0.497, 3.055)	0.653
Tumor location: HRL; LRL	1.523 (0.937, 2.476)	0.090
Puncture method: FNP technique; CP technique	2.205 (1.021, 4.761)	0.044	2.596 (1.197, 5.631)	0.016

AFP: Alpha-fetoprotein; CP: Conventional puncture; ECOG PS: Eastern Cooperative Oncology Group performance status rating; FNP: Fine needle-assisted puncture positioning; HRL: High-risk location; LRL: Low-risk location; MWA: Microwave ablation; TACE: Transarterial chemoembolization.