Safety and feasibility of irreversible electroporation for the pancreatic head in a porcine model

Figure 5 Histopathology of the duodenum wall after irreversible electroporation. A: The duodenum wall showed necrosis and focal hemorrhage in the mucosa, submucosa, and muscle layers 1 h after irreversible electroporation (IRE); B: The mucosal layer was congested with massive infiltration of inflammatory cells 24 h after IRE; C: On 7 d after IRE new villous structures were observed in the mucosal layer, and immature muscle cells were seen in the muscle layer; D: Twenty-eight days after IRE, the structure of the duodenum appeared intact, and the mucosa layer returned to normal thickness. Scale bars in A-D = 200 μm.