Influence of SCENIC recommendations on terminology used for histopathologic diagnosis of inflammatory bowel disease-associated dysplasia

Table 5 Comparison of serrated epithelial change diagnosed on random endoscopic biopsies from ulcerative colitis patients between pre-SCENIC (2012-2014) and post-SCENIC (2016-2018) periods

		Pre-SCENIC		Post-SCENIC
		Hyperplastic change (%)	SEC	Hyperplastic change (%)	SEC	SSA/P
Total		47	2	61	3	2
Location	Right	2 (4.3)	0	5 (8.2)	0	1
	Transverse	2 (4.3)	0	3 (4.9)	0	1
	Left	17 (36.2)	2	14 (23.0)	1	0
	Rectum	16 (34.0)	0	31 (50.8)	0	0
	Multiple sites	10 (21.3)	0	8 (13.1)	2	0
Synchronous adenoma/dysplasia
	TA	41 (8.5)	11	5 (8.2)	0	0
	LGD	42 (8.5)	0	2 (3.3)	0	0
	SSA/P	0	0	1 (1.6)	1	0
No. of cases with follow-up biopsies		33	2	31	3	1
Metachronous dysplasia
	TVA	11 (3.0)	0	1 (3.2)	0	0
	TA	1 (3.0)	1	61 (19.4)	0	0
	LGD	3 (9.1)	0	2 (6.5)	0	0
	SSA/P	1 (3.0)	0	1 (3.2)	0	0
	IND	0	0	1 (3.2)	0	0

¹One case had multiple adenomas.

²Two cases had multiple foci of LGD.

SCENIC: Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients; SEC: Serrated epithelial change; SSA/P: Sessile serrated adenoma/polyp; TA: Tubular adenoma; TVA: Tubulovillous adenoma; LGD: Low-grade dysplasia; IND: Indefinite for dysplasia.