KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling

Figure 3 KIFC3 promotes the progression of cell cycle in ESCC cells. A: Cell cycle analysis showing that KIFC3 knockdown induces cell cycle arrest in KYSE150 cells; B: Cell cycle analysis showing that KIFC3 overexpression promotes the progression of cell cycle in KYSE450 cells; C: Western blotting showing that KIFC3 knockdown decreases the expression of cyclin D1 in KYSE150 cells, while KIFC3 overexpression increased the expression of cyclin D1 in KYSE450 cells; D: Statistical analysis of the data presented in C. ^aP < 0.05 versus the control group. ESCC: Esophageal squamous cell carcinoma; KIFC3: Kinesin family member C3.