KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling

Figure 2 KIFC3 promotes proliferation in human ESCC cells. A: Colony-formation assay shows that KIFC3 knockdown inhibits colony formation in KYSE150 cells; B: Colony-formation assay shows that KIFC3 overexpression promotes colony formation in KYSE450 cells; C: EdU proliferation assay shows that KIFC3 knockdown inhibits proliferation in KYSE150 cells, while its overexpression promotes proliferation in KYSE450 cells, scale bar: 20 μm; D: Statistical analysis of the data shown in C; E: Western blotting shows that KIFC3 promotes the expression of proliferating cell nuclear antigen in ESCC cells. ^aP < 0.05 versus the control group. ESCC: Esophageal squamous cell carcinoma; KIFC3: Kinesin family member C3.