KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling

Figure 1 KIFC3 is overexpressed in ESCC tissues and is associated with poor prognosis. A: Immunohistochemistry shows that KIFC3 is overexpressed in ESCC tissues compared with adjacent normal tissues, scale bar: 500 μm; B: Kaplan–Meier Plotter shows that high levels of KIFC3 are associated with poor prognosis in ESCC patients; C: Western blotting shows expression of KIFC3 in ESCC cell lines and normal esophageal epithelial cell line Het-1A; D: Western blotting shows that KIFC3-knockdown and KIFC3-overexpressed cell lines are constructed successfully. ESCC: Esophageal squamous cell carcinoma; KIFC3: Kinesin family member C3.