Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors

Table 3 Univariate and multivariate analyses of predictors for high-grade dysplasia /carcinoma

	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
LST subtype
NG-FE	1	-	1	-
NG-PD	18.4 (7.4-45.4)	< 0.001	16.8 (6.5-43.5)	< 0.001
G-NM	10.4 (5.3-20.6)	< 0.001	7.8 (3.8-16.1)	< 0.001
G-H	1.3 (0.6-2.9)	0.504	1.1 (0.5-2.4)	0.871
Location
Non-rectosigmoid	1	-
Rectosigmoid	2.3 (1.5-3.7)	< 0.001
Size, cm
< 2	1	-	1	-
≥ 2	2.6 (1.6-4.0)	< 0.001	2.2 (1.3-3.9)	0.005
Non-lifting sign
Negative	1	-	1	-
Positive	4.0 (1.6-9.8)	0.003	3.3 (1.2-9.2)	0.024

LST: Laterally spreading tumor; G-NM: Granular nodular mixed; G-H: Granular homogenous; NG-FE: Non-granular flat elevated; NG-PD: Non-granular pseudodepressed; OR: Odds ratio; CI: Confidence interval.