Gut microbiome and pancreatic cancer cachexia: An evolving relationship

Table 1 Consensus definitions of cancer cachexia[5]

Definition of cancer cachexia is met with one of the following
Weight loss > 5% over past 6 mo (in absence of simple starvation)
Body mass index < 20 and weight loss > 2%
Evidence of sarcopenia with weight loss > 2%1

¹Generally accepted measures of sarcopenia include: mid upper-arm muscle area by anthropometry (men < 32 cm², women < 18 cm²); appendicular skeletal muscle index determined by dual energy x-ray absorptiometry (men < 7.26 kg/m²; women < 5.45 kg/m²); lumbar skeletal muscle index determined by computed tomography imaging (men < 55 cm²/m²; women < 39 cm²/m²); whole body fat-free mass index without bone determined by bioelectrical impedance (men < 14.6 kg/m²; women < 11.4 kg/m²).