Retrospective Cohort Study
Copyright ©The Author(s) 2022.
World J Gastrointest Oncol. Jun 15, 2022; 14(6): 1148-1161
Published online Jun 15, 2022. doi: 10.4251/wjgo.v14.i6.1148
Table 2 Tumor characteristics and surgical quality by surgical approach

Open (n = 19830)
Laparoscopic (n = 12144)
Robotic (n = 6953)
Total (n = 38927)
P value
Clinical stage< 0.0011
II9286 (46.8%)5477 (45.1%)2906 (41.8%)17669 (45.4%)
III10544 (53.2%)6667 (54.9%)4047 (58.2%)21258 (54.6%)
Pathological stage< 0.0011
0508 (3.2%)323 (3.4%)222 (3.9%)1053 (3.4%)
13801 (23.8%)2736 (28.7%)1669 (29.6%)8206 (26.3%)
25416 (33.9%)2941 (30.8%)1669 (29.6%)10026 (32.2%)
36107 (38.2%)3480 (36.5%)2044 (36.3%)11631 (37.3%)
4152 (1.0%)57 (0.6%)29 (0.5%)238 (0.8%)
Chemotherapy sequence< 0.0011
No chemotherapy 2031 (10.2%)1397 (11.5%)459 (6.6%)3887 (10.0%)
Chemotherapy after surgery1864 (9.4%)1210 (10.0%)421 (6.1%)3495 (9.0%)
Chemotherapy before and after surgery5435 (27.4%)3691 (30.4%)2256 (32.4%)11382 (29.2%)
Chemotherapy before surgery10481 (52.9%)5840 (48.1%)3810 (54.8%)20131 (51.7%)
Radiation sequence< 0.0011
No radiation2449 (12.3%)1713 (14.1%)651 (9.4%)4813 (12.4%)
Radiation after surgery1470 (7.4%)911 (7.5%)315 (4.5%)2696 (6.9%)
Radiation before surgery15911 (80.2%)9515 (78.4%)5987 (86.1%)31418 (80.7%)
Total neoadjuvant therapy2194 (28.1%)1262 (25.1%)846 (28.0%)4302 (27.1%)< 0.0011
Surgery type< 0.0011
TME with sphincter preservation12118 (61.1%)8633 (71.1%)4986 (71.7%)25737 (66.1%)
TME without sphincter preservation7061 (35.6%)2760 (22.7%)1927 (27.7%)11748 (30.2%)
Conversion to open0 (0.0%)1760 (14.5%)480 (6.9%)2240 (11.7%)< 0.0011
Residual tumor< 0.0011
R018012 (91.9%)11174 (93.6%)6568 (95.1%)35754 (93.0%)
R1806 (4.1%)413 (3.5%)193 (2.8%)1412 (3.7%)
R2782 (4.0%)352 (2.9%)148 (2.1%)1282 (3.3%)
Number of lymph nodes examined (mean ± SD)14.7 ± 9.714.8 ± 9.815.7 ± 9.014.9 ± 9.6< 0.0011
12 or more lymph nodes examined13198 (67.1%)8148 (67.7%)5088 (73.6%)26434 (68.4%)< 0.0011