Prognostic significance of serum inflammation indices for different tumor infiltrative pattern types of gastric cancer

Table 1 Baseline characteristics of the patients

Characteristics	INFa (n = 183)	INFb (n = 331)	INFc (n = 448)
Sex
Male	133 (72.7)	248 (74.9)	308 (68.8)
Female	50 (27.3)	83 (25.1)	140 (31.2)
Age (yr)	58.81 ± 9.59	59.30 ± 9.73	57.06 ± 10.55
Borrmann type
0-1	31 (16.9)	51 (15.4)	21 (4.7)
2	62 (33.9)	105 (31.7)	104 (23.2)
3	74 (40.4)	138 (41.7)	242 (54.0)
4-5	16 (8.8)	37 (11.2)	81 (18.1)
Tumor location
Lower third	156 (85.2)	227 (68.6)	329 (73.4)
Middle third	21 (11.5)	64 (19.3)	75 (16.8)
Upper third	4 (2.2)	33 (10.0)	31 (6.9)
Entire stomach	2 (1.1)	7 (2.1)	13 (2.9)
Tumor size (mm)	44.40 ± 24.85	53.06 ± 25.78	56.31 ± 27.38
pTNM stage
I	72 (39.3)	70 (21.1)	36 (8.0)
II	60 (32.8)	127 (38.4)	137 (30.6)
III	51 (27.9)	134 (40.5)	275 (61.4)
Histological type
Well and medium differentiation	112 (61.2)	149 (45.0)	126 (28.1)
Poor differentiation	46 (25.1)	88 (26.6)	207 (46.2)
Others	25 (13.7)	94 (28.4)	115 (25.7)
mLNR	0.09 ± 0.16	0.12 ± 0.17	0.19 ± 0.22
Vascular infiltration
No	137 (74.9)	231 (69.8)	317 (70.8)
Yes	46 (25.1)	100 (30.2)	131 (29.2)
Nerve infiltration
No	123 (67.2)	198 (59.8)	251 (56.0)
Yes	60 (32.8)	133 (40.2)	197 (44.0)
Postoperative chemotherapy
Yes	58 (31.7)	90 (27.2)	167 (37.3)
No	125 (68.3)	241 (72.8)	281 (62.7)

Tumor infiltrative pattern, tumor location, postsurgical tumor node metastasis stage, histological type, mLNR, vascular infiltration and nerve infiltration were according to the postoperative pathology report. INF: Tumor infiltrative pattern; INFa: Expansive growth type; INFb: Intermediate type; INFc: Infiltrative growth type; mLNR: Metastatic lymph node ratio; pTNM: Postsurgical tumor node metastasis.