Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways

Figure 6 The effect of frankincense and/or myrrh on collagen IV (400×). A: Immunofluorescence staining of the tumor was indicated by collagen IV antibody (green); B: The relative expression of collagen IV. Scale bars: 100 μm. LF: Low dose of frankincense extract; HF: High dose of frankincense extract; LM: Low dose of myrrh extract; HM: High dose of myrrh extract; LFM: Low dose of frankincense + myrrh extracts; HFM: High dose of frankincense + myrrh extracts. Data represents the mean ± SE. Compared with the model control, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.