Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways

Figure 5 The effect of frankincense and/or myrrh on CD31 and α-SMA (200×). A: Immunofluorescence staining of the tumor was indicated by CD31 antibody (red) and α-SMA antibody (green); B: The relative expression of CD31; C: The expression of α-SMA/CD31. Scale bars: 100 μm. LF: Low dose of frankincense extract; HF: High dose of frankincense extract; LM: Low dose of myrrh extract; HM: High dose of myrrh extract; LFM: Low dose of frankincense + myrrh extracts; HFM: High dose of frankincense + myrrh extracts. Data represents the mean ± SE. ^aP < 0.05 vs the model control; ^bP < 0.05 vs ZD1839; ^cP < 0.05 vs high dose of frankincense + myrrh extracts.