Copyright
©The Author(s) 2022.
World J Gastrointest Oncol. Feb 15, 2022; 14(2): 375-395
Published online Feb 15, 2022. doi: 10.4251/wjgo.v14.i2.375
Published online Feb 15, 2022. doi: 10.4251/wjgo.v14.i2.375
Figure 6 Genome instability.
Colibactin is a genotoxin associated with particular strains of Escherichia coli. Sulfidogenic bacteria referred to in this diagram are Fusobacterium, Desulfovibrio and Bilophila wadsworthia. ROS: Reactive oxygen species; RNS: Reactive nitrogen species; H2S: Hydrogen sulfide; CIN: Chromosomal instability; BFT: Bacteroides fragilis toxin; MSI: Microsatellite instability; MAPK: Mitogen-activated protein kinase; COX-2: Cyclooxygenase-2.
- Citation: Tortora SC, Bodiwala VM, Quinn A, Martello LA, Vignesh S. Microbiome and colorectal carcinogenesis: Linked mechanisms and racial differences. World J Gastrointest Oncol 2022; 14(2): 375-395
- URL: https://www.wjgnet.com/1948-5204/full/v14/i2/375.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v14.i2.375