Edema of limbs as the primary symptom of gastric signet-ring cell carcinoma: A case report and literature review

Table 1 Characteristics of laboratory examinations

Parameter	Initial visit	3 mo	12 mo	Reference value range
Full blood count
White cell count as × 109/L	6.4	7.55	3.58	(3.5-9.5)
Neutrophils as × 109/L	4.51	5.56	2.25	(1.8-6.3)
Lymphocytes as × 109/L	1.3	1.32	0.68	(1.1-3.2)
Monocytes as × 109/L	0.36	0.5	0.23	(0.1-0.6)
Platelets as × 109/L	218	223	208	(125-350)
Hemoglobin in g/L	144	136	157	(130-175)
Tumor markers
Carbohydrate antigen 724 in U/mL	16.41	15.51	15.67	(< 6.9)
Carbohydrate antigen 199 in U/mL	15.88	16.84	4.43	(≤ 34)
Carcinoembryonic antigen in ng/mL)	2.81	2.86	0.78	(≤ 5)
Blood biochemical indicators
Alanine aminotransferase in U/L	16	11	14	(≤ 41)
Aspartate aminotransferase in U/L	13	13	15	(≤ 41)
Globulin in g/L	28.9	25.5	19	(64-83)
Albumin in g/L	38.2	32.2	25	(35-52)
Creatine kinase in U/L	93	56	24	(≤ 190)
Lactic dehydrogenase in U/L	163	156	202	(135-225)
Urea nitrogen in mmol/L	8.97	12.54	12.83	(3.1-8.0)
Creatinine in μmol/L	126	130	152	(59-104)
Estimated glomerular filtration rate in mL/min/1.73 m2	55	52.9	49.5	(> 90)
Random blood glucose in mmol/L	6.22	5.39	6.12	(< 11.1)
Serum potassium in mmol/L	4.2	3.88	3.89	(3.5-5.1)
Serum sodium in mmol/L	141.5	141	142	(136-145)
Cardiac troponin T in pg/mL	2.2	2.5	2.7	(≤ 34.2)
N terminal pro B type natriuretic peptide in pg/mL	53	45	59	(< 161)
Fibrinogen in g/L	4.31	5.03	5.88	(2-4)
D-Dimer in μg/mL FEU	1.36	1.05	7.19	(< 0.5)
Other indicators
Antinuclear antibodies	1:100	1:100	Not available	(negative)
Immunoglobulin IgG in g/L	9.31	8.57	9.27	(7-16)
Complement C3 in g/L	1.46	1.32	1.39	(0.8-1.8)
Complement C4 in g/L	0.67	0.39	0.51	(0.1-0.4)
Erythrocyte sedimentation rate in mm/h	20	21	25	(0-15)
High sensitivity C-reactive protein in mg/L	5.52	6.43	6.83	(0-5)
Interleukin 6 in pg/mL	2.72	3.56	2.98	(0.1-2.9)
Tumor necrosis factor α in pg/mL	2.07	2.97	3.12	(0.1-23)
T lymphocyte (CD3 + CD19 -) as /μL	830	977	780	(955-2860)
B lymphocyte (CD3 + CD19 -), as /μL	62	84	52	(90-560)
Proteinuria	negative	negative	negative	(negative)
Antineutrophil cytoplasmic antibody	negative	negative	negative	(negative)
Procalcitonin	< 0.05	< 0.05	< 0.05	(< 0.05)