KLF16 promotes pancreatic adenocarcinoma cell proliferation and migration by positively regulating SMAD6

Figure 2 Krüppel-like factor 16 regulates pancreatic adenocarcinoma cell proliferation. A, B: The efficiency of Krüppel-like factor (KLF)16 knockdown in pancreatic adenocarcinoma (PAAD) cells by (A) qPCR and (B) western blotting. GAPDH used as the internal control; C, D: Cell proliferation of PAAD cells after KLF16 knockdown. (E, F) Colony numbers of PAAD cells after KLF16 knockdown; G, H: The efficiency of KLF16 overexpression in the cells by (G) qPCR and (H) western blotting. GAPDH used as the internal control; I, J: Cell proliferation of PAAD cells after KLF16 overexpression by the CCK-8 assay; K, L: Colony numbers of PAAD cells after KLF16 overexpression by colony formation assay. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001.