Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development

Table 5 Multiple logistic regression results (odds ratios and 95%CIs) for the risk of colon polyp development in comparison to the control group¹

	Odds ratio	95%CI	P value
Antioxidants
Vitamin Α, per 99.6 μg/L	8.84	3.76-20.74	< 0.001
Vitamin C, per 2.8 μg/L	0.99	0.58-1.70	0.982
Vitamin E, per 0.7 mg/L	1.51	0.87-2.63	0.141
Vitamin D, per 8.2 ng/mL	0.27	0.15-0.48	< 0.001
Se, per 13.6 μg/L	1.68	0.82-3.42	0.157
Zn, per 128.5 μg/L	0.39	0.16-0.94	0.036
B12, per 157.1 pg/L	1.51	0.92-2.46	0.103
Folic acid, per 38.1 ng/L	1.42	0.74-2.72	0.299
Οxidants
Malondialdehyde, per 0.5 μmol/L	0.35	0.20-0.60	< 0.001
Fe2+, per 33.9 μg/dL	2.58	1.53-4.33	< 0.001

¹Controlling for age, sex, serum triglycerides, and smoking habits. Se: Selenium; Zn: Zinc; B12: Vitamin B12/cobalamin; Fe²⁺: Ferum.