Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development

Table 4 Results from multiple logistic regression models (odds ratios and 95%CIs) for the risk of colon adenocarcinoma in comparison to the control group¹

	Odds ratio	95%CI	P value
Antioxidants
Vitamin Α, per 99.6 μg/L	1.20	0.77-1.88	0.430
Vitamin C, per 2.8 μg/L	0.71	0.44-1.15	0.168
Vitamin E, per 0.7 mg/L	0.57	0.39-0.84	0.004
Vitamin D, per 8.2 ng/mL	0.04	0.02-0.12	< 0.001
Se, per 13.6 μg/L	0.35	0.22-0.55	< 0.001
Zn, per 128.5 μg/L	0.16	0.09-0.31	< 0.001
B12, per 157.1 pg/L	0.80	0.51-1.26	0.337
Folic acid, per 38.1 ng/L	0.77	0.54-1.11	0.170
Oxidants
Malondialdehyde, per 0.5 μmol/L	2.09	1.27-3.45	0.004
Fe2+, per 33.9 μg/dL	0.73	0.47-1.13	0.154

¹Controlling for age, sex, serum triglycerides, and smoking habits. Se: Selenium; Zn: Zinc; B12: Vitamin B12/cobalamin; Fe²⁺: Ferum.