Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development

Table 3 Percent change (and 95%CIs respectively) in the levels of serum antioxidant and oxidant substances compared to the control group

	Colon polyps	Colon adenocarcinoma
	% Change (95%CI)	% Change (95%CI)
Antioxidants
Antioxidant capacity	-40.1 (-41.6 to -38.5)	-40.7 (-41.8 to -39.5)
Vitamin Α	32.2 (20.8 to 44.7)	0.1 (-6.9 to 7.6)
Vitamin C	-3.1 (-15.8 to 11.6)	-12.7 (-21.9 to -2.4)
Vitamin E	4.2 (-5.0 to 14.2)	-12.3 (-18.4 to -5.7)
Vitamin D	-46.0 (-54.9 to -35.4)	-56.8 (-62.6 to -50.2)
Se	1.7 (-6.3 to 10.4)	-19.4 (-24.5 to -14.0)
Zn	-6.7 (-12.9 to 0.0)	-20.2 (-24.5 to -15.7)
B12	6.0 (-11.7 to 27.2)	-15.0 (-26.5 to -1.8)
Folic acid	2.1 (-6.9 to 12.0)	-8.2 (-14.7 to -1.3)
Oxidants
Oxidant activity	120.1 (111.7 to 128.9)	113.4 (106.8 to 120.2)
Malondialdehyde	-31.6 (-39.8 to -22.3)	10.1 (-0.6 to 21.9)
Fe2+	43.5 (22.2 to 68.5)	-8.9 (-19.8 to 3.5)

Results from multiple log-linear regression models controlling for age, sex, serum triglycerides, and smoking habits.