Cuproptosis-related long non-coding RNAs model that effectively predicts prognosis in hepatocellular carcinoma

Figure 8 Gene set functional annotation of differentially expressed genes and long-chain non-coding RNAs in high- and low-risk hepatocellular carcinoma groups. A: In gene ontology analysis, differentially expressed genes and long-chain non-coding RNAs (lncRNAs) were found to be most enriched in biological process terms mitotic nuclear division, mitotic sister chromatid segregation, nuclear division, chromosome segregation, and sister chromatid segregation; in cellular component terms condensed chromosomes, kinetochores, spindles, chromosomes, and condensed chromosomes; and in molecular function terms steroid hydroxylase activity, oxidoreductase activity, microtubule binding, aromatase activity, and tubulin binding; B: Differentially expressed genes and lncRNAs were found to be most enriched in the following five Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways: retinol metabolism, cytochrome P450 drug metabolism, cytochrome P450 xenobiotic metabolism, cell cycle, and chemical carcinogenesis-DNA adducts. BP: Biological process; CC: Cellular component; MF: Molecular function.