Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells

Figure 2 Interleukin-34 modulates clone formation and proliferation in AGS cells. A and B: Downregulation of endogenous interleukin (IL)-34 reduced the mean colony number in the colony formation assay; C: Downregulation of endogenous IL-34 reduced the mean number of AGS cells in the proliferation assay; D and E: Upregulation of endogenous COL5A2 increased the number of invasion cells in the colony formation assay; F: Upregulation of endogenous IL-34 increased the mean number of AGS cells in the proliferation assay. Data shown on graphs were obtained from three independent replicates of the experiments and expressed as mean ± SD, ^aP < 0.05, ^bP < 0.01.