Transcriptional factor III A promotes colorectal cancer progression by upregulating cystatin A

Figure 3 Knockdown of transcriptional factor III A gene inhibits the invasion and migration of colorectal cancer cell in vitro. A: The migratory abilities of short hairpin (sh) GTF3A#1 and #4-HCT116 cells were detected using wound-healing assay (a1). The migratory abilities of shGTF3A#1 and #4-SW480 cells were detected as above (a2); B: The migratory and invasive capabilities of shGTF3A#1 and #4-HCT116 (b1) and shGTF3A#1 and #4-SW480 cells (b2) were detected using transwell assay. The migrated and invaded cells were counted (b3). Migratory and invasive capabilities are expressed as the mean ± SEM of three independent experiments. ^cP < 0.001.