Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival

Figure 4 Receiver operating curve analyses for overall survival and Kaplan-Meier curves for optimal cutoff values in right-sided colorectal cancer patients for significant predictors. A-B: CD8⁺-lymphocyte (CD8)_{peritumour (pt)}, worse below 8.25; C-D: CD4⁺ plus CD8⁺-lymphocyte (CD4CD8)_pt worse below 10.16; E-F: Lymphocyte-to-monocyte ratio (LMR)_pt worse below 3.185; G-H: CD8⁺-lymphocyte-to-monocyte ratio (CD8MR)_pt worse below 1.65; I-J: LMR_b/LMR_pt worse above 0.985; K-L: LMR_{blood (b)}/ CD8⁺-lymphocyte-to-monocyte ratio_pt worse above 1.485; survival proportions at 26 mo after surgery (median follow-up) are shown (^aP < 0.05, ^bP < 0.01, log-rank test).