Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model

Figure 2 Effects of hydrogen and 5-fluorouracil on the oxidative stress index in colorectal cancer. A: Malondialdehyde; B: Total thiol; C: Superoxide dismutase; D: Catalase activity. P < 0.05, P < 0.01 and P < 0.001 compared to control, P < 0.05 and P < 0.001 compared to 5-fluorouracil, P < 0.001 compared to hydrogen groups; n = 6 per group. a: P < 0.05 compare to control; b: P < 0.01 compare to control; c: P < 0.001 compare to control; d: P < 0.05 compare to H₂; e: P < 0.001 compare to H₂; f: P < 0.001 compare to 5-FU. H₂: Hydrogen; 5-FU: 5-fluorouracil; SOD: Superoxide dismutase; MDA: Malondialdehyde; CAT: Catalase.