Review
Copyright ©The Author(s) 2022.
World J Gastrointest Oncol. Jan 15, 2022; 14(1): 90-109
Published online Jan 15, 2022. doi: 10.4251/wjgo.v14.i1.90
Table 4 Examples of biomarkers in gastric cancer
Genes
Purpose
Findings
Ref.
RUNX3Diagnosis/prognosisMethylation status correlates with liver metastasis[155]
MLH1Diagnosis/prognosisMethylation status correlates with tumor stage[156]
RASSF1ADiagnosis/prognosisMethylation status correlates with advanced stage, and lymph node positivity[157]
MGMTDiagnosis/prognosisMethylation status correlates with distant metastasis[156]
ANOS1DiagnosisExpression correlates with tumor progression[158]
RPRMLPrognosisExpression correlates with survival[159]
CTD-2510F5.4Diagnosis/prognosisExpression correlates with clinicopathological classification and survival[160]
lncRNA-GC1DiagnosisCirculating exosomal level correlates with early detection and disease progression[161]
mesothelinDiagnosisExpression correlates with Peritoneal Recurrence[162]
MiR-379-5pMiR-410-3pPrognosisExpression correlates with metastasis[163]
S100A9Diagnosis /PrognosisExpression correlates with tumor aggressiveness[164]
Notch1/2/3/4PrognosisExpression correlates with immune infiltration[165]
KAT2ADiagnosisExpression correlates with depth of tumor invasion and tumor stage[166]