Gastric cancer: An epigenetic view

doi:10.4251/wjgo.v14.i1.90

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2022; 14(1): 90-109
Published online Jan 15, 2022. doi: 10.4251/wjgo.v14.i1.90

Table 4 Examples of biomarkers in gastric cancer

Genes	Purpose	Findings	Ref.
RUNX3	Diagnosis/prognosis	Methylation status correlates with liver metastasis	[155]
MLH1	Diagnosis/prognosis	Methylation status correlates with tumor stage	[156]
RASSF1A	Diagnosis/prognosis	Methylation status correlates with advanced stage, and lymph node positivity	[157]
MGMT	Diagnosis/prognosis	Methylation status correlates with distant metastasis	[156]
ANOS1	Diagnosis	Expression correlates with tumor progression	[158]
RPRML	Prognosis	Expression correlates with survival	[159]
CTD-2510F5.4	Diagnosis/prognosis	Expression correlates with clinicopathological classification and survival	[160]
lncRNA-GC1	Diagnosis	Circulating exosomal level correlates with early detection and disease progression	[161]
mesothelin	Diagnosis	Expression correlates with Peritoneal Recurrence	[162]
MiR-379-5pMiR-410-3p	Prognosis	Expression correlates with metastasis	[163]
S100A9	Diagnosis /Prognosis	Expression correlates with tumor aggressiveness	[164]
Notch1/2/3/4	Prognosis	Expression correlates with immune infiltration	[165]
KAT2A	Diagnosis	Expression correlates with depth of tumor invasion and tumor stage	[166]

Citation: Tang SY, Zhou PJ, Meng Y, Zeng FR, Deng GT. Gastric cancer: An epigenetic view. World J Gastrointest Oncol 2022; 14(1): 90-109
URL: https://www.wjgnet.com/1948-5204/full/v14/i1/90.htm
DOI: https://dx.doi.org/10.4251/wjgo.v14.i1.90