Gastric cancer: An epigenetic view

Table 1 Important miRNAs and their targets and biological functions in gastric cancer

miRNAs	Expression	Targets	Functions	Ref.
miR-21	Up	EMT	Tumor growth, metastasis	[89]
miR-183	Up	UVRAG	Cell proliferation, autophagy, apoptosis	[90]
miR-765	Up	BATF2	Chemosensitivity	[91]
miR-155	Up	TP53INP1	Cell cycle, proliferation, migration	[92]
miR-130b	Up	NFκB, p65	Cell proliferation, tumorigenesis	[93]
miR-92a-1-5p	Up	FOXD1	Metaplasia	[94]
miR-135b	Up	FOXN3/RECK	Cell invasion, CSC-like properties	[95]
miR-181a-5p	Up	AKT3	Cell proliferation, apoptosis, tumor growth	[96]
miR-224	Up	PAK4	Cell proliferation, migration	[97]
let-7i	Down	COL1A1	Cell invasion, metastasis	[98]
miR-146a	Down	-	Cell migration	[99]
MiR-12129	Down	SIRT1	Cell cycle, proliferation	[100]
miR-27b	Down	NR2F2	cell proliferation, tumor growth	[101]
miR-140-5p	Down	NOTCH1	Cell proliferation, migration, apoptosis	[102]
miR-34a	Down	Snail	Cell proliferation, invasion	[103]
miR-9	Down	TNFAIP8L3	Cell proliferation, migration	[104]
miR-195	Down	HMGB1	Chemosensitivity	[105]