Exosomes as potential diagnosis and treatment for liver cancer

Table 4 As a carrier for drug treatment

Drugs	Source of exosomes	Animal model (Yes/No)	Clinical sample (Yes/No)	Functions	Ref.
Norcantharidin	BMSCs-exosomes	Y	N	Induce cell cycle arrest, reduced tumor cell proliferation, increased apoptosis	[67]
siGRP78	BMSCs-exosomes	Y	N	Sensitize Sorafenib resistant cancer cells to Sorafenib	[68]
miR-214	hCEC-exosomes	N	Y (n = 6)	Enhances the anti-tumor efficacy of oxaliplatin and sorafenib on HCC cells	[69]

BMSCs: Bone marrow mesenchymal stem cell; hCEC: Human cerebral endothelial cell; HCC: Hepatocellular carcinoma.