Screening strategy for gastrointestinal and hepatopancreatobiliary cancers in cystic fibrosis

Table 1 Epidemiology of gastrointestinal cancers in the cystic fibrosis population

Type of cancer	Incidence rate (per 100000 CF per year)	Odds ratio (95%CI)	Standardized incidence ratio (95%CI)	Ref.
Colorectal
Colon	39	-	10.91 (8.42-14.11)	Yamada et al[5]
Rectum	-	-	0.5 (0.0-2.6)	Maisonneuve et al[3]
Pancreatic	1-5.8	31.5 (4.8-205)	6.18 (1.31-29.27)	Neglia et al[4], Yamada et al[5], Maisonneuve et al[8]
Liver
Biliary tract	5.1	-	17.87 (8.55-37.36)	Yamada et al[5]
Stomach	-	-	4.5 (1.2-12.3)	Maisonneuve et al[3]
Esophagus	-	14.3 (1.4-148)	2.8 (0.1-13.8)	Maisonneuve et al[3], Neglia et al[4]
Small bowel	13	-	18.94 (9.37-38.27)	Yamada et al[5]

Odds ratio and standardized incidence ratio are comparing cancers in cystic fibrosis versus cancers in the general population. CF: Cystic fibrosis; CI: C interval.