Development of a prognostic prediction model based on microRNA-1269a in esophageal cancer

Table 3 Gene Ontology enrichment analysis of microRNA-1269a target genes

ID	Term	Gene	Count	P value
GO:0005515	Protein binding	CLTC, WDR6, PUM2, MATR3, AKAP11, SMARCA4, UBN1, YWHAZ, BSDC1, SMG1, ZNF146, BACH2, KHSRP, TPM3, TAGLN2, PTBP1, PHKG2, TNPO2, MAP1A, ZBTB4, HMGCR, AP3D1, FN1, PTMA, TBP, CCND2, NCL, CDK6, SEC61A1	29	3.58E-11
GO:0005829	Cytosol	YWHAZ, MAP1A, CCND2, SMG1, WDR1, PTMA, ZBTB4, BACH2, KHSRP, TPM3, CLTC, SEC61A1, PUM2, WDR6, CDK6, AKAP11, TAGLN2, PHKG2, ZNF146	19	3.79E-09
GO:0005634	Nucleus	YWHAZ, ZNF146, CCND2, SMG1, MATR3, PTMA, ZBTB4, BACH2, SLC25A1, KHSRP, NCL, CDK6, TBP, PTBP1, SMARCA4, UBN1, TNPO2	17	3.02E-07
GO:0005654	Nucleoplasm	YWHAZ, CCND2, SMG1, PTMA, ZBTB4, BACH2, KHSRP, NCL, CDK6, TBP, PTBP1, SMARCA4, UBN1	13	5.25E-06
GO:0005737	Cytoplasm	YWHAZ, MAP1A, CCND2, SMG1, WDR6, TBP, KHSRP, PUM2, CDK6, AKAP11, TNPO2	11	0.0013
GO:0070062	Extracellular exosome	YWHAZ, FN1, WDR1, SLC25A1, KHSRP, TPM3, NCL, CLTC, PGAM1, PTBP1, TAGLN2	11	8.89E-07
GO:0003723	RNA binding	YWHAZ, WDR6, SMG1, CLTC, KHSRP, PUM2, NCL, MATR3, PTBP1, SMARCA4	10	1.64E-07
GO:0016020	Membrane	CLTC, KHSRP, SEC61A1, NCL, MATR3, PTBP1, SMARCA4, AP3D1	8	0.00032
GO:0042802	Identical protein binding	YWHAZ, HMGCR, FN1, KHSRP, NCL, MATR3	6	0.00144
GO:0005730	Nucleolus	ZNF146, KHSRP, SMARCA4, UBN1, ZBTB4	5	7.83E-05
GO:0003677	DNA binding	ZNF146, CCND2, NCL, AKAP11, PTBP1, SMARCA4	6	0.00369
GO:0000122	Negative regulation of transcription by RNA polymerase II	BACH2, SMARCA4, CDK6, ZBTB4	4	0.00569
GO:0019901	Protein kinase binding	YWHAZ, CCND2, CLTC, ZBTB4	4	0.00067
GO:0003729	mRNA binding	PUM2, PTBP1, KHSRP, MATR3	4	2.90E-05
GO:0032991	Protein-containing complex	TBP, SMARCA4, CLTC	3	0.01671
GO:0043066	Negative regulation of apoptotic process	YWHAZ, CCND2, PTMA	3	0.00866
GO:0006468	Protein phosphorylation	YWHAZ, PHKG2, CDK6	3	0.00703
GO:0098978	Glutamatergic synapse	YWHAZ, AP3D1, NPTX1	3	0.00361
GO:0019899	Enzyme binding	TBP, PHKG2, FN1	3	0.00358
GO:0051301	Cell division	CCND2, CLTC, CDK6	3	0.00339
GO:0008134	Transcription factor binding	YWHAZ, TBP, SMARCA4	3	0.00285
GO:0001525	Angiogenesis	YWHAZ, NCL, FN1	3	0.00118
GO:0030054	Cell junction	KHSRP, SLC7A2, WDR1	3	0.00062
GO:0005198	Structural molecule activity	MAP1A, CLTC, MATR3	3	0.00043
GO:0043488	Regulation of mRNA stability	YWHAZ, PUM2, KHSRP	3	0.00013